Therapeutic Drug Concentrations

Therapeutic Drug Concentrations

DrugsLabel NameSpecimenReference values in Serum
AmitriptylineSaroten, TryptizolS-: 300-700 nmol/L
AmlodipineAmlodipin, NorvascS-: 0,025 mg/L
AtenololAtenolol, TenorminS-: 0,54 mg/L
Citalopram Citalopram, Cipralex.S-:20-800 nmol/L
DigoxinLanacristS-: <1,4 nmol/L
Phenytoin EpanutinS-: 40-80 µmol/L
FlecainideTambocorS-: 0,5-2,0 µmol/L
FluoxetinFontexS-: 100-1940 nmol/L
GentamicinGentamicin, GaramycinS-: 1.5-4.0 mg/L 8 hours after administration.
Carbamazepin TegretolS-: 20-40 µmol/L
Clomipramin AnafranilS-: 550-1300 nmol/L (klomipramin + desmetylklomipramin)
Clonazepam IktorivilS-: 35-60-(120) µmol/L
LitiumLithionitS-: 0,5 -0,8 mmol/L, ibland 0,9-1,2 mmol/L
LamotriginLamictalP-: 12-56 µmol/L
LevetiracetamKeppraP-: 35-120 µmol/L
Meropenemanhydrat MeronemS-: 8-10 µg/mL
Mirtazapin Mirtazapin, RemeronS-: 35-520 nmol/L
Olanzapin Olanzapine, ZyprexaS-: 15-300 nmol/L
OxazepamOxazepam, OxascandS-: 0,7-4,2 µmol/L.
ParacetamolAlvedon, Panodil, RelivS-: Reference value not detectable. In case of intoxication, sampling, interpretation of test results and treatment should be in accordance with the Poison Information Center's guidelines.
ParoxetineParoxetine, SeroxatS-: 20-600 nmol/L
PropranololPropranolol, InderalS-: 0,075-0,1 mg/L
QuetiapinSeroquelS-: 50-700 nmol/L
Risperidon Risperidone, RisperdalS-: 50-150 nmol/L
Salicylates Trombyl, Treo, Magnecyl, Bamyl, AspirineS-: 1,1-2,2 mmol/L (Adults)
Sertraline Sertraline, SeroxatS-: 10-525 nmol/L
TacrolimusPrografB-: 5-20 µg/L
Theophylline Theophylline, Theo-DurS-: 55-110 µmol/L
TobramycinNebcinS-: The lowest value should not exceed 2 mg/L. In a test taken 1 hour after initiation of administration, the concentration should be at least 4 mg/L and not more than 12 mg/L.
TopiramatTopimaxS-: 15-60 µmol/L.
ValproateErgenylS-: 350-700 µmol/L
Vancomycine VancocinS-: The lowest value should not exceed 15 mg/L. Samples taken 1 hour after completion of infusion should not exceed 50 mg/L.
VenlafaxineEfexorS-: 50-900 nmol/L
ZuclopentixolCisordinolS-: 7-30 nmol/L
Please observe different units for different drugs